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Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro.
The effects of cholera toxin (CT) and 8-chloro-cAMP (8-Cl-cAMP) on cell growth were investigated using two human pancreatic carcinoma cell lines (MIA PaCa-2, Panc-1). CT, which catalyses the ADP ribosylation of Gs, suppresses the proliferation of MIA PaCa-2(PC) cells. CT at the low dose of 0.1 pg ml...
Autores principales: | Ohmura, E., Wakai, K., Isozaki, O., Murakami, H., Onoda, N., Emoto, N., Shizume, K., Tsushima, T., Demura, H., Robins, R. K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968158/ https://www.ncbi.nlm.nih.gov/pubmed/8381655 |
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