Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.

The Syrian hamster embryo cell lines, SHOK and MC-1, were used as recipient cells for DNA transfection assay to detect transforming genes in experimental mouse tumours. A mouse repeat sequence was utilised to check whether each transformed focus included mouse genomic DNA in the Hamster background....

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Autores principales: Sasai, H., Higashi, T., Nakamori, S., Miyoshi, J., Suzuki, F., Nomura, T., Kakunaga, T.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968199/
https://www.ncbi.nlm.nih.gov/pubmed/8431357
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author Sasai, H.
Higashi, T.
Nakamori, S.
Miyoshi, J.
Suzuki, F.
Nomura, T.
Kakunaga, T.
author_facet Sasai, H.
Higashi, T.
Nakamori, S.
Miyoshi, J.
Suzuki, F.
Nomura, T.
Kakunaga, T.
author_sort Sasai, H.
collection PubMed
description The Syrian hamster embryo cell lines, SHOK and MC-1, were used as recipient cells for DNA transfection assay to detect transforming genes in experimental mouse tumours. A mouse repeat sequence was utilised to check whether each transformed focus included mouse genomic DNA in the Hamster background. We investigated five mouse tumours that are related to X-ray radiation, and detected activated c-K-ras, c-mos, and c-cot oncogenes which induced foci of hamster cells. These results show that SHOK and MC-1 cells have unique properties for detecting transforming genes in experimental mouse tumours. IMAGES:
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spelling pubmed-19681992009-09-10 Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours. Sasai, H. Higashi, T. Nakamori, S. Miyoshi, J. Suzuki, F. Nomura, T. Kakunaga, T. Br J Cancer Research Article The Syrian hamster embryo cell lines, SHOK and MC-1, were used as recipient cells for DNA transfection assay to detect transforming genes in experimental mouse tumours. A mouse repeat sequence was utilised to check whether each transformed focus included mouse genomic DNA in the Hamster background. We investigated five mouse tumours that are related to X-ray radiation, and detected activated c-K-ras, c-mos, and c-cot oncogenes which induced foci of hamster cells. These results show that SHOK and MC-1 cells have unique properties for detecting transforming genes in experimental mouse tumours. IMAGES: Nature Publishing Group 1993-02 /pmc/articles/PMC1968199/ /pubmed/8431357 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Sasai, H.
Higashi, T.
Nakamori, S.
Miyoshi, J.
Suzuki, F.
Nomura, T.
Kakunaga, T.
Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.
title Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.
title_full Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.
title_fullStr Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.
title_full_unstemmed Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.
title_short Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours.
title_sort syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in x-ray-related mouse tumours.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968199/
https://www.ncbi.nlm.nih.gov/pubmed/8431357
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