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Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group.
Six hundred and eighty-four primary breast cancers from the International (Ludwig) Breast Cancer Study Group (IBCSG) were studied for Helix pomatia lectin (HPA) binding. There was a weak correlation between lymph node-positive and HPA positive (P = 0.04). In our series there was a large advantage in...
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Lenguaje: | English |
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Nature Publishing Group
1993
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968298/ https://www.ncbi.nlm.nih.gov/pubmed/8318406 |
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collection | PubMed |
description | Six hundred and eighty-four primary breast cancers from the International (Ludwig) Breast Cancer Study Group (IBCSG) were studied for Helix pomatia lectin (HPA) binding. There was a weak correlation between lymph node-positive and HPA positive (P = 0.04). In our series there was a large advantage in disease-free survival (DFS) and overall survival (OS) for node-negative patients (P < 0.0001 DFS and OS). However, there was no such advantage for HPA-negative patients (P = 0.23 DFS and P = 0.32 OS). We conclude that in this randomised patient group HPA is of no clinical predictive value. IMAGES: |
format | Text |
id | pubmed-1968298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1993 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-19682982009-09-10 Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. Br J Cancer Research Article Six hundred and eighty-four primary breast cancers from the International (Ludwig) Breast Cancer Study Group (IBCSG) were studied for Helix pomatia lectin (HPA) binding. There was a weak correlation between lymph node-positive and HPA positive (P = 0.04). In our series there was a large advantage in disease-free survival (DFS) and overall survival (OS) for node-negative patients (P < 0.0001 DFS and OS). However, there was no such advantage for HPA-negative patients (P = 0.23 DFS and P = 0.32 OS). We conclude that in this randomised patient group HPA is of no clinical predictive value. IMAGES: Nature Publishing Group 1993-07 /pmc/articles/PMC1968298/ /pubmed/8318406 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. |
title | Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. |
title_full | Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. |
title_fullStr | Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. |
title_full_unstemmed | Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. |
title_short | Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group. |
title_sort | prognostic value of helix pomatia in breast cancer. international (ludwig) breast cancer study group. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968298/ https://www.ncbi.nlm.nih.gov/pubmed/8318406 |