Long term survival of small cell lung cancer patients after chemotherapy.

Eighty-one patients with small cell lung cancer (SCLC) with a survival of more than 2 years after start of chemotherapy were studied. Twenty-six of the 28 patients who died of relapsed SCLC had in fact relapsed before two years and of the 55 who had not then only two (4%) relapsed subsequently. It i...

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Autores principales: van der Gaast, A., Postmus, P. E., Burghouts, J., van Bolhuis, C., Stam, J., Splinter, T. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968359/
https://www.ncbi.nlm.nih.gov/pubmed/8385981
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author van der Gaast, A.
Postmus, P. E.
Burghouts, J.
van Bolhuis, C.
Stam, J.
Splinter, T. A.
author_facet van der Gaast, A.
Postmus, P. E.
Burghouts, J.
van Bolhuis, C.
Stam, J.
Splinter, T. A.
author_sort van der Gaast, A.
collection PubMed
description Eighty-one patients with small cell lung cancer (SCLC) with a survival of more than 2 years after start of chemotherapy were studied. Twenty-six of the 28 patients who died of relapsed SCLC had in fact relapsed before two years and of the 55 who had not then only two (4%) relapsed subsequently. It is stressed that with such observations treatment related factors should be taken in account. Second tumours were observed in ten patients, nine proven malignant. Of the eight patients with non-small cell lung cancer three had residual disease after initial chemotherapy. In our patient group after a 2 year disease-free interval the risk of developing non-small cell lung cancer seems higher than a subsequent relapse of SCLC.
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spelling pubmed-19683592009-09-10 Long term survival of small cell lung cancer patients after chemotherapy. van der Gaast, A. Postmus, P. E. Burghouts, J. van Bolhuis, C. Stam, J. Splinter, T. A. Br J Cancer Research Article Eighty-one patients with small cell lung cancer (SCLC) with a survival of more than 2 years after start of chemotherapy were studied. Twenty-six of the 28 patients who died of relapsed SCLC had in fact relapsed before two years and of the 55 who had not then only two (4%) relapsed subsequently. It is stressed that with such observations treatment related factors should be taken in account. Second tumours were observed in ten patients, nine proven malignant. Of the eight patients with non-small cell lung cancer three had residual disease after initial chemotherapy. In our patient group after a 2 year disease-free interval the risk of developing non-small cell lung cancer seems higher than a subsequent relapse of SCLC. Nature Publishing Group 1993-04 /pmc/articles/PMC1968359/ /pubmed/8385981 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
van der Gaast, A.
Postmus, P. E.
Burghouts, J.
van Bolhuis, C.
Stam, J.
Splinter, T. A.
Long term survival of small cell lung cancer patients after chemotherapy.
title Long term survival of small cell lung cancer patients after chemotherapy.
title_full Long term survival of small cell lung cancer patients after chemotherapy.
title_fullStr Long term survival of small cell lung cancer patients after chemotherapy.
title_full_unstemmed Long term survival of small cell lung cancer patients after chemotherapy.
title_short Long term survival of small cell lung cancer patients after chemotherapy.
title_sort long term survival of small cell lung cancer patients after chemotherapy.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968359/
https://www.ncbi.nlm.nih.gov/pubmed/8385981
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