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Tumour necrotisation in nude mice xenografts by the reversible protein synthesis inhibitor zilascorb(2H).
The deuterated benzaldehyde derivative zilascorb(2H), 5,6-O-benzylidene-d-L-ascorbic acid, was administered once daily by i.v. injection in nude mice with grafted tumours of a human malignant melanoma (E.E.) and ovarian carcinoma (OVCAR-3) origins. Like benzaldehyde, zilascorb(2H) has been shown to...
Autores principales: | Pettersen, E. O., Larsen, R. O., Dornish, J. M., Børretzen, B., Juul, M. E., Aastveit, T. E., Nesland, J. M., Rofstad, E. K., Oftebro, R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968361/ https://www.ncbi.nlm.nih.gov/pubmed/8471421 |
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