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The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment.

Flunarizine is a class IV calcium channel blocker which increases oxygen delivery to hypoxic regions in solid tumours, exerting a radiosensitising effect in vivo in animal tumour models. Precisely how the drug improves oxygenation is not well understood. We hypothesised that metabolic conditions pre...

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Detalles Bibliográficos
Autores principales: Kavanagh, B. D., Coffey, B. E., Needham, D., Hochmuth, R. M., Dewhirst, M. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968366/
https://www.ncbi.nlm.nih.gov/pubmed/8471430

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