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Interim analyses and stopping rules in cancer clinical trials.
A clinical trial conducted according to a schedule of interim analyses written into the protocol, and stopped according to a predetermined rule, is known to statisticians as a sequential clinical trial. This methodology is becoming more widely used in trials concerning life-threatening diseases beca...
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| Formato: | Texto |
| Lenguaje: | English |
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Nature Publishing Group
1993
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968667/ https://www.ncbi.nlm.nih.gov/pubmed/8260370 |