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L1210 cells selected for resistance to methoxymorpholinyl doxorubicin appear specifically resistant to this class of morpholinyl derivatives.

We investigated the mechanism of resistance in murine L1210 leukaemia cells selected after treatment with FCE 23762 methoxymorpholinyl doxorubicin: (MMRDX), a methoxymorpholinyl derivative of doxorubicin active in vitro and in vivo on multidrug-resistant (mdr) cells, currently undergoing phase I cli...

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Detalles Bibliográficos
Autores principales:	Geroni, C., Pesenti, E., Broggini, M., Belvedere, G., Tagliabue, G., D'Incalci, M., Pennella, G., Grandi, M.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1994
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968686/ https://www.ncbi.nlm.nih.gov/pubmed/8297727

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