Effectiveness of HB2 (anti-CD7)--saporin immunotoxin in an in vivo model of human T-cell leukaemia developed in severe combined immunodeficient mice.

The transplantation of the human T-cell acute lymphoblastic leukaemia (T-ALL) cell line HSB-2 into severe combined immunodeficient (SCID) mice was found to produce a disseminated pattern of leukaemia similar to that seen in man. The intravenous injection of 10(7) HSB-2 cells was associated with a un...

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Detalles Bibliográficos
Autores principales: Morland, B. J., Barley, J., Boehm, D., Flavell, S. U., Ghaleb, N., Kohler, J. A., Okayama, K., Wilkins, B., Flavell, D. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968696/
https://www.ncbi.nlm.nih.gov/pubmed/7507691

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