Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.

We studied 100 patients with non-Hodgkin's lymphoma, 44 patients with Hodgkin's disease and 100 controls for the prevalence of the EcoRI restriction fragment polymorphism of the L-myc oncogene. No difference in the frequency of the three genotypes (LL, LS, SS) was found between the patient...

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Autores principales: Crossen, P. E., Morrison, M. J., Colls, B. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968797/
https://www.ncbi.nlm.nih.gov/pubmed/7908219
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author Crossen, P. E.
Morrison, M. J.
Colls, B. M.
author_facet Crossen, P. E.
Morrison, M. J.
Colls, B. M.
author_sort Crossen, P. E.
collection PubMed
description We studied 100 patients with non-Hodgkin's lymphoma, 44 patients with Hodgkin's disease and 100 controls for the prevalence of the EcoRI restriction fragment polymorphism of the L-myc oncogene. No difference in the frequency of the three genotypes (LL, LS, SS) was found between the patient and control groups. However, the S allele was found to occur more frequently in the non-Hodgkin's lymphoma patients (chi 2 = 4.57, P = 0.032). These data confirm an earlier report and suggest that the presence of the S allele is associated with susceptibility to non-Hodgkin's lymphoma.
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spelling pubmed-19687972009-09-10 Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma. Crossen, P. E. Morrison, M. J. Colls, B. M. Br J Cancer Research Article We studied 100 patients with non-Hodgkin's lymphoma, 44 patients with Hodgkin's disease and 100 controls for the prevalence of the EcoRI restriction fragment polymorphism of the L-myc oncogene. No difference in the frequency of the three genotypes (LL, LS, SS) was found between the patient and control groups. However, the S allele was found to occur more frequently in the non-Hodgkin's lymphoma patients (chi 2 = 4.57, P = 0.032). These data confirm an earlier report and suggest that the presence of the S allele is associated with susceptibility to non-Hodgkin's lymphoma. Nature Publishing Group 1994-04 /pmc/articles/PMC1968797/ /pubmed/7908219 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Crossen, P. E.
Morrison, M. J.
Colls, B. M.
Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.
title Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.
title_full Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.
title_fullStr Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.
title_full_unstemmed Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.
title_short Increased frequency of the S allele of the L-myc oncogene in non-Hodgkin's lymphoma.
title_sort increased frequency of the s allele of the l-myc oncogene in non-hodgkin's lymphoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968797/
https://www.ncbi.nlm.nih.gov/pubmed/7908219
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AT morrisonmj increasedfrequencyofthesalleleofthelmyconcogeneinnonhodgkinslymphoma
AT collsbm increasedfrequencyofthesalleleofthelmyconcogeneinnonhodgkinslymphoma

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