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A pilot study to evaluate the effects of C1 esterase inhibitor on the toxicity of high-dose interleukin 2.

In a pilot study six patients received 4 days' treatment with interleukin 2 (IL-2) [cumulative dose (CD) 264 +/- 26 x 10(6) IU m-2] and C1 esterase inhibitor (C1-INH) (loading dose 2,000 U, followed by 500-1,000 U twice daily). Toxicity was compared with that in patients given 4 days' trea...

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Detalles Bibliográficos
Autores principales: Ogilvie, A. C., Baars, J. W., Eerenberg, A. J., Hack, C. E., Pinedo, H. M., Thijs, L. G., Wagstaff, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968861/
https://www.ncbi.nlm.nih.gov/pubmed/8123494