The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.

Anticipatory nausea and vomiting (ANV) after repeated cycles of cytotoxic chemotherapy is thought to be a conditioned response to a conditioning stimulus. Good control of acute and delayed emesis may result in a lower incidence of ANV. We have analysed data from 574 chemotherapy patients who receive...

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Autores principales: Aapro, M. S., Kirchner, V., Terrey, J. P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968891/
https://www.ncbi.nlm.nih.gov/pubmed/8180031
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author Aapro, M. S.
Kirchner, V.
Terrey, J. P.
author_facet Aapro, M. S.
Kirchner, V.
Terrey, J. P.
author_sort Aapro, M. S.
collection PubMed
description Anticipatory nausea and vomiting (ANV) after repeated cycles of cytotoxic chemotherapy is thought to be a conditioned response to a conditioning stimulus. Good control of acute and delayed emesis may result in a lower incidence of ANV. We have analysed data from 574 chemotherapy patients who received granisetron as their antiemetic treatment during repeat cycle chemotherapy. Per treatment cycle, less than 10% of patients displayed symptoms of anticipatory nausea and 2% or less had symptoms of anticipatory vomiting. It is concluded that the use of granisetron as an antiemetic during the acute phase of chemotherapy may result in a lower incidence of ANV in patients undergoing repeat cycle chemotherapy.
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spelling pubmed-19688912009-09-10 The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron. Aapro, M. S. Kirchner, V. Terrey, J. P. Br J Cancer Research Article Anticipatory nausea and vomiting (ANV) after repeated cycles of cytotoxic chemotherapy is thought to be a conditioned response to a conditioning stimulus. Good control of acute and delayed emesis may result in a lower incidence of ANV. We have analysed data from 574 chemotherapy patients who received granisetron as their antiemetic treatment during repeat cycle chemotherapy. Per treatment cycle, less than 10% of patients displayed symptoms of anticipatory nausea and 2% or less had symptoms of anticipatory vomiting. It is concluded that the use of granisetron as an antiemetic during the acute phase of chemotherapy may result in a lower incidence of ANV in patients undergoing repeat cycle chemotherapy. Nature Publishing Group 1994-05 /pmc/articles/PMC1968891/ /pubmed/8180031 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Aapro, M. S.
Kirchner, V.
Terrey, J. P.
The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
title The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
title_full The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
title_fullStr The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
title_full_unstemmed The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
title_short The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
title_sort incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968891/
https://www.ncbi.nlm.nih.gov/pubmed/8180031
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