Multidrug resistance circumvention by a new triazinoaminopiperidine derivative S9788 in vitro: definition of the optimal schedule and comparison with verapamil.

The current work was undertaken to investigate the importance of exposure sequence and duration in achieving the maximum reversal action of S9788 on doxorubicin (DOX) cytotoxicity against cells that exhibit the (MDR) multidrug resistance phenotype: the MCF7/DOX cell line. Accumulation and release of...

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Detalles Bibliográficos
Autores principales: Julia, A. M., Roché, H., Berlion, M., Lucas, C., Milano, G., Robert, J., Bizzari, J. P., Canal, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1968895/
https://www.ncbi.nlm.nih.gov/pubmed/8180016

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