Effect of 5-fluorouracil combination therapy on RNA processing in human colonic carcinoma cells.

We have evaluated the RNA-directed cytotoxicity of 5-fluorouracil (5-FU) in human colonic carcinoma cells. The mode of action of 5-FU and its effects on human pre-rRNA processing were then examined. From these data, possible reasons why the disruption of pre-rRNA maturation could induce cytotoxic ef...

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Detalles Bibliográficos
Autores principales: Greenhalgh, D. A., Parish, J. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971286/
https://www.ncbi.nlm.nih.gov/pubmed/2328208

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