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Synergism between 5-fluorouracil and N-methylformamide in HT29 human colon cancer line.
In HT29 cells 5-fluorouracil (5FU) cytotoxicity is enhanced by subsequent incubation of cells in medium containing 1% N-methylformamide (NMF). This enhancement does not appear to be related to differences in the repair of 5FU-induced DNA damage. It is proposed that the inhibition of DNA synthesis by...
Autores principales: | Laudonio, N., Zupi, G., Erba, E., Leonetti, C., D'Incalci, M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1990
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971307/ https://www.ncbi.nlm.nih.gov/pubmed/2328201 |
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