Fatty acid control of growth of human cervical and endometrial cancer cells.

Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhib...

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Autores principales: Gleeson, R. P., Ayub, M., Wright, J. T., Wood, C. B., Habib, N. A., Soutter, W. P., Sullivan, M. H., White, J. O.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971358/
https://www.ncbi.nlm.nih.gov/pubmed/2331435
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author Gleeson, R. P.
Ayub, M.
Wright, J. T.
Wood, C. B.
Habib, N. A.
Soutter, W. P.
Sullivan, M. H.
White, J. O.
author_facet Gleeson, R. P.
Ayub, M.
Wright, J. T.
Wood, C. B.
Habib, N. A.
Soutter, W. P.
Sullivan, M. H.
White, J. O.
author_sort Gleeson, R. P.
collection PubMed
description Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor number or affinity.
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spelling pubmed-19713582009-09-10 Fatty acid control of growth of human cervical and endometrial cancer cells. Gleeson, R. P. Ayub, M. Wright, J. T. Wood, C. B. Habib, N. A. Soutter, W. P. Sullivan, M. H. White, J. O. Br J Cancer Research Article Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor number or affinity. Nature Publishing Group 1990-04 /pmc/articles/PMC1971358/ /pubmed/2331435 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Gleeson, R. P.
Ayub, M.
Wright, J. T.
Wood, C. B.
Habib, N. A.
Soutter, W. P.
Sullivan, M. H.
White, J. O.
Fatty acid control of growth of human cervical and endometrial cancer cells.
title Fatty acid control of growth of human cervical and endometrial cancer cells.
title_full Fatty acid control of growth of human cervical and endometrial cancer cells.
title_fullStr Fatty acid control of growth of human cervical and endometrial cancer cells.
title_full_unstemmed Fatty acid control of growth of human cervical and endometrial cancer cells.
title_short Fatty acid control of growth of human cervical and endometrial cancer cells.
title_sort fatty acid control of growth of human cervical and endometrial cancer cells.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971358/
https://www.ncbi.nlm.nih.gov/pubmed/2331435
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