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Investigation of the relationship between altered intracellular pH and multidrug resistance in mammalian cells.
The intracellular pH of a number of multidrug resistant cell lines was compared with that of their parental lines using the fluorescent probe bis-carboxyethylcarboxyfluorescein. In four different cases, cells having 5-fold resistance or more exhibited an intracellular pH which was 0.10-0.17 units hi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1990
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971365/ https://www.ncbi.nlm.nih.gov/pubmed/2158805 |