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P388 leukaemia cells resistant to the anthracycline menogaril lack multidrug resistant phenotype.

Menogaril is an anthracycline presently in Phase II clinical trials. Menogaril-resistant mouse leukaemia P388 cells were developed in vitro by 4 months of exposure to step-wise increasing concentrations of menogaril after which resistant cells (P388/MEN) were cloned in 320 ng ml-1 menogaril. P388/ME...

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Detalles Bibliográficos
Autores principales:	Badiner, G. J., Moy, B. C., Smith, K. S., Tarpley, W. G., Groppi, V. E., Bhuyan, B. K.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1990
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971454/ https://www.ncbi.nlm.nih.gov/pubmed/2145026

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