Intrathecal administration of 131I radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.

Fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mCi of a 131I radiolabelled monoclonal antibody (MoAb), chosen for its immunoreactivity to tumour. Major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone ma...

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Detalles Bibliográficos
Autores principales: Moseley, R. P., Davies, A. G., Richardson, R. B., Zalutsky, M., Carrell, S., Fabre, J., Slack, N., Bullimore, J., Pizer, B., Papanastassiou, V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971477/
https://www.ncbi.nlm.nih.gov/pubmed/2223581

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