Cargando…
Distribution of pimonidazole and RSU 1069 in tumour and normal tissues.
The tritium-labelled analogues of pimonidazole and RSU 1069 were injected into mice bearing the KHT murine sarcoma which has a hypoxic cell fraction of approximately 10%. The distribution of activity at 24 h was recorded using autoradiography and measurement of tissue activity. Autoradiographs with...
Autores principales: | Cobb, L. M., Nolan, J., Butler, S. A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1990
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971577/ https://www.ncbi.nlm.nih.gov/pubmed/2257219 |
Ejemplares similares
-
Potentiation of RSU-1069 tumour cytotoxicity by 5-hydroxytryptamine (5-HT).
por: Chaplin, D. J.
Publicado: (1986) -
Studies of the in vivo and in vitro cytotoxicity of the drug RSU-1069.
por: Hill, R. P., et al.
Publicado: (1986) -
Pharmacokinetics and cytotoxicity of RSU-1069 in subcutaneous 9L tumours under oxic and hypoxic conditions.
por: Wong, K. H., et al.
Publicado: (1991) -
Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. II. RSU 1069.
por: Olive, P. L.
Publicado: (1995) -
Radiation sensitization and chemopotentiation: RSU 1069, a compound more efficient than misonidazole in vitro and in vivo.
por: Adams, G. E., et al.
Publicado: (1984)