The use of duplex sonography in the detection of colorectal hepatic metastases.

Conventional imaging techniques are of limited value in identifying small liver metastases. Indirect methods of measuring blood-flow have shown that metastases may be associated with subtle changes in liver blood-flow. Doppler ultrasonography has the ability to measure liver blood-flow directly. In...

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Autores principales: Leen, E., Goldberg, J. A., Robertson, J., Sutherland, G. R., McArdle, C. S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971785/
https://www.ncbi.nlm.nih.gov/pubmed/1997115
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author Leen, E.
Goldberg, J. A.
Robertson, J.
Sutherland, G. R.
McArdle, C. S.
author_facet Leen, E.
Goldberg, J. A.
Robertson, J.
Sutherland, G. R.
McArdle, C. S.
author_sort Leen, E.
collection PubMed
description Conventional imaging techniques are of limited value in identifying small liver metastases. Indirect methods of measuring blood-flow have shown that metastases may be associated with subtle changes in liver blood-flow. Doppler ultrasonography has the ability to measure liver blood-flow directly. In this study, the role of duplex sonography in the detection of hepatic metastases was evaluated. Hepatic arterial and portal venous blood-flows were measured in 30 patients awaiting surgery for colorectal cancer and 16 controls. The ratio of hepatic arterial: portal venous blood-flow (Doppler flow ratio; DFR) and the ratio of hepatic arterial:hepatic arterial and portal venous blood-flow (Doppler perfusion index; DPI) were calculated. Clear separation of the DPI and DFR values of controls and patients with histologically confirmed liver metastases was observed (P less than 0.001). The data suggest that the measurement of liver blood-flow by duplex sonography may be of value in the diagnosis of colorectal liver metastases.
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spelling pubmed-19717852009-09-10 The use of duplex sonography in the detection of colorectal hepatic metastases. Leen, E. Goldberg, J. A. Robertson, J. Sutherland, G. R. McArdle, C. S. Br J Cancer Research Article Conventional imaging techniques are of limited value in identifying small liver metastases. Indirect methods of measuring blood-flow have shown that metastases may be associated with subtle changes in liver blood-flow. Doppler ultrasonography has the ability to measure liver blood-flow directly. In this study, the role of duplex sonography in the detection of hepatic metastases was evaluated. Hepatic arterial and portal venous blood-flows were measured in 30 patients awaiting surgery for colorectal cancer and 16 controls. The ratio of hepatic arterial: portal venous blood-flow (Doppler flow ratio; DFR) and the ratio of hepatic arterial:hepatic arterial and portal venous blood-flow (Doppler perfusion index; DPI) were calculated. Clear separation of the DPI and DFR values of controls and patients with histologically confirmed liver metastases was observed (P less than 0.001). The data suggest that the measurement of liver blood-flow by duplex sonography may be of value in the diagnosis of colorectal liver metastases. Nature Publishing Group 1991-02 /pmc/articles/PMC1971785/ /pubmed/1997115 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Leen, E.
Goldberg, J. A.
Robertson, J.
Sutherland, G. R.
McArdle, C. S.
The use of duplex sonography in the detection of colorectal hepatic metastases.
title The use of duplex sonography in the detection of colorectal hepatic metastases.
title_full The use of duplex sonography in the detection of colorectal hepatic metastases.
title_fullStr The use of duplex sonography in the detection of colorectal hepatic metastases.
title_full_unstemmed The use of duplex sonography in the detection of colorectal hepatic metastases.
title_short The use of duplex sonography in the detection of colorectal hepatic metastases.
title_sort use of duplex sonography in the detection of colorectal hepatic metastases.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971785/
https://www.ncbi.nlm.nih.gov/pubmed/1997115
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