Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.

Mothers of a population-based series of young adults with bone and soft tissue sarcoma were traced and their cancer risks estimated. No overall excess of cancers compared with expected numbers calculated from population rates was seen but mothers of patients with synovial sarcoma had significantly m...

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Detalles Bibliográficos
Autores principales: Hartley, A. L., Birch, J. M., Blair, V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971866/
https://www.ncbi.nlm.nih.gov/pubmed/2003983
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author Hartley, A. L.
Birch, J. M.
Blair, V.
author_facet Hartley, A. L.
Birch, J. M.
Blair, V.
author_sort Hartley, A. L.
collection PubMed
description Mothers of a population-based series of young adults with bone and soft tissue sarcoma were traced and their cancer risks estimated. No overall excess of cancers compared with expected numbers calculated from population rates was seen but mothers of patients with synovial sarcoma had significantly more cancers than expected and this was accounted for mainly by an excess of breast cancer. In addition there were strong indications that a proportion of cases were members of families with inherited cancer-prone syndromes, in particular with neurofibromatosis or with the Li Fraumeni cancer family syndrome.
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spelling pubmed-19718662009-09-10 Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas. Hartley, A. L. Birch, J. M. Blair, V. Br J Cancer Research Article Mothers of a population-based series of young adults with bone and soft tissue sarcoma were traced and their cancer risks estimated. No overall excess of cancers compared with expected numbers calculated from population rates was seen but mothers of patients with synovial sarcoma had significantly more cancers than expected and this was accounted for mainly by an excess of breast cancer. In addition there were strong indications that a proportion of cases were members of families with inherited cancer-prone syndromes, in particular with neurofibromatosis or with the Li Fraumeni cancer family syndrome. Nature Publishing Group 1991-03 /pmc/articles/PMC1971866/ /pubmed/2003983 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Hartley, A. L.
Birch, J. M.
Blair, V.
Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
title Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
title_full Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
title_fullStr Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
title_full_unstemmed Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
title_short Malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
title_sort malignant disease in the mothers of a population-based series of young adults with bone and soft tissue sarcomas.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1971866/
https://www.ncbi.nlm.nih.gov/pubmed/2003983
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AT birchjm malignantdiseaseinthemothersofapopulationbasedseriesofyoungadultswithboneandsofttissuesarcomas
AT blairv malignantdiseaseinthemothersofapopulationbasedseriesofyoungadultswithboneandsofttissuesarcomas

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