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Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells

BACKGROUND: Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells play an essential role in the host defence against intracellular pathogens such as Listeria, and Mycobacteria. The key mediator of bacteria-directed cytotoxicity is granulysin, a 9 kDa protein stored in cytolytic granules togeth...

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Detalles Bibliográficos
Autores principales:	Walch, Michael, Latinovic-Golic, Sonja, Velic, Ana, Sundstrom, Hanna, Dumrese, Claudia, Wagner, Carsten A, Groscurth, Peter, Ziegler, Urs
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976101/ https://www.ncbi.nlm.nih.gov/pubmed/17705829 http://dx.doi.org/10.1186/1471-2172-8-14

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