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Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

BACKGROUND: Induction of apoptosis is one strategy for treatment of prostate cancer. The Shb adapter protein has been found to regulate apoptosis in various cell types and consequently human prostate cancer 3 (PC3) cells were transfected to obtain cells overexpressing Shb in order to increase our un...

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Detalles Bibliográficos
Autores principales: Davoodpour, Padideh, Landström, Maréne, Welsh, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976127/
https://www.ncbi.nlm.nih.gov/pubmed/17697368
http://dx.doi.org/10.1186/1471-2407-7-161