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Quantitative sequence-function relationships in proteins based on gene ontology

BACKGROUND: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function – the basis of transfer of annotations in databases – must therefore be regarded with caution. Here, we present a quanti...

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Detalles Bibliográficos
Autores principales: Sangar, Vineet, Blankenberg, Daniel J, Altman, Naomi, Lesk, Arthur M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976327/
https://www.ncbi.nlm.nih.gov/pubmed/17686158
http://dx.doi.org/10.1186/1471-2105-8-294

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