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Quantitative sequence-function relationships in proteins based on gene ontology
BACKGROUND: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function – the basis of transfer of annotations in databases – must therefore be regarded with caution. Here, we present a quanti...
Autores principales: | Sangar, Vineet, Blankenberg, Daniel J, Altman, Naomi, Lesk, Arthur M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976327/ https://www.ncbi.nlm.nih.gov/pubmed/17686158 http://dx.doi.org/10.1186/1471-2105-8-294 |
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