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Impact of polysialylated CD56 on natural killer cell cytotoxicity
BACKGROUND: Siglec-7, a sialic acid binding inhibitory receptor expressed by NK cells is masked in vivo by a so far unknown ligand. It shows a strong binding prevalence for α-2,8-linked disialic acids in vitro. RESULTS: Here we describe the expression of PSA-NCAM (α-2,8-linked polysialic acid modifi...
Autores principales: | Moebius, Jeannette M, Widera, Darius, Schmitz, Juergen, Kaltschmidt, Christian, Piechaczek, Christoph |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976417/ https://www.ncbi.nlm.nih.gov/pubmed/17683591 http://dx.doi.org/10.1186/1471-2172-8-13 |
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