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Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae
DNA double-strand breaks can be repaired by illegitimate recombination without extended sequence homology. A distinct mechanism namely microhomology-mediated recombination occurs between a few basepairs of homology that is associated with deletions. Ionizing radiation and restriction enzymes have be...
Autores principales: | Chan, Cecilia Y., Kiechle, Markus, Manivasakam, Palaniyandi, Schiestl, Robert H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976441/ https://www.ncbi.nlm.nih.gov/pubmed/17652322 http://dx.doi.org/10.1093/nar/gkm442 |
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