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Local selection rules that can determine specific pathways of DNA unknotting by type II DNA topoisomerases

We performed numerical simulations of DNA chains to understand how local geometry of juxtaposed segments in knotted DNA molecules can guide type II DNA topoisomerases to perform very efficient relaxation of DNA knots. We investigated how the various parameters defining the geometry of inter-segmenta...

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Detalles Bibliográficos
Autores principales:	Burnier, Yannis, Weber, Cedric, Flammini, Alessandro, Stasiak, Andrzej
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976442/ https://www.ncbi.nlm.nih.gov/pubmed/17670794 http://dx.doi.org/10.1093/nar/gkm532

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