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An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination

Peptide bond formation and peptidyl-tRNA hydrolysis are the two elementary chemical reactions of protein synthesis catalyzed by the ribosomal peptidyl transferase ribozyme. Due to the combined effort of structural and biochemical studies, details of the peptidyl transfer reaction have become increas...

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Detalles Bibliográficos
Autores principales: Amort, Melanie, Wotzel, Brigitte, Bakowska-Zywicka, Kamilla, Erlacher, Matthias D., Micura, Ronald, Polacek, Norbert
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976462/
https://www.ncbi.nlm.nih.gov/pubmed/17660192
http://dx.doi.org/10.1093/nar/gkm539

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