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An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination
Peptide bond formation and peptidyl-tRNA hydrolysis are the two elementary chemical reactions of protein synthesis catalyzed by the ribosomal peptidyl transferase ribozyme. Due to the combined effort of structural and biochemical studies, details of the peptidyl transfer reaction have become increas...
Autores principales: | Amort, Melanie, Wotzel, Brigitte, Bakowska-Zywicka, Kamilla, Erlacher, Matthias D., Micura, Ronald, Polacek, Norbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976462/ https://www.ncbi.nlm.nih.gov/pubmed/17660192 http://dx.doi.org/10.1093/nar/gkm539 |
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