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Chromatin Structure Regulates Gene Conversion

Homology-directed repair is a powerful mechanism for maintaining and altering genomic structure. We asked how chromatin structure contributes to the use of homologous sequences as donors for repair using the chicken B cell line DT40 as a model. In DT40, immunoglobulin genes undergo regulated sequenc...

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Detalles Bibliográficos
Autores principales: Cummings, W. Jason, Yabuki, Munehisa, Ordinario, Ellen C, Bednarski, David W, Quay, Simon, Maizels, Nancy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976632/
https://www.ncbi.nlm.nih.gov/pubmed/17880262
http://dx.doi.org/10.1371/journal.pbio.0050246