Sensitization of normal and malignant tissue to cyclophosphamide by nitroimidazoles with different partition coefficients.

The ability of a range of 2-nitroimidazoles with similar electron affinities but widely differing partition coefficients (P) to enhance the cytotoxicity of cyclophosphamide (CY) in mouse tumour and normal tissues was investigated. In a preliminary study large single doses of benznidazole (BENZ), mis...

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Detalles Bibliográficos
Autores principales: Hirst, D. G., Hazlehurst, J. L., Brown, J. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1984
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976681/
https://www.ncbi.nlm.nih.gov/pubmed/6229264

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