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Effects of the induction of hepatic microsomal metabolism on the toxicity of cyclophosphamide.

Cyclophosphamide (CP) administration to rats in a single i.p. dose (200 mg kg-1), while producing urinary bladder toxicity and 30-40% depression of the hepatic microsomal mixed function oxidase (MFO), failed to produce any depression of MFO activities in extrahepatic tissues such as lung, kidney and...

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Detalles Bibliográficos
Autores principales: Gurtoo, H. L., Bansal, S. K., Pavelic, Z., Struck, R. F.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1985
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976820/
https://www.ncbi.nlm.nih.gov/pubmed/3966972