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Effects of the antioestrogen tamoxifen on the cell cycle kinetics of the human breast cancer cell line, MCF-7.

The effect of 10(-6) M tamoxifen on MCF-7 cells adapted to growth in 0.5% foetal calf serum has been studied. The growth inhibitory effect of this tamoxifen concentration was abolished by simultaneous addition of 10(-8) M oestradiol, indicating that tamoxifen may exert its effect via binding to the...

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Detalles Bibliográficos
Autores principales: Lykkesfeldt, A. E., Larsen, J. K., Christensen, I. J., Briand, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1984
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976853/
https://www.ncbi.nlm.nih.gov/pubmed/6733020