Neurotensin in human small cell lung carcinoma.

High levels of neurotensin-like immunoreactivity were found in human small cell lung carcinoma lines. No immunoreactivity was present in non-small cell carcinoma lines and only low amounts in postmortem human lung tissue. The immunoreactive material co-eluted with synthetic neurotensin on two differ...

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Autores principales: Goedert, M., Reeve, J. G., Emson, P. C., Bleehen, N. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1984
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976878/
https://www.ncbi.nlm.nih.gov/pubmed/6087865
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author Goedert, M.
Reeve, J. G.
Emson, P. C.
Bleehen, N. M.
author_facet Goedert, M.
Reeve, J. G.
Emson, P. C.
Bleehen, N. M.
author_sort Goedert, M.
collection PubMed
description High levels of neurotensin-like immunoreactivity were found in human small cell lung carcinoma lines. No immunoreactivity was present in non-small cell carcinoma lines and only low amounts in postmortem human lung tissue. The immunoreactive material co-eluted with synthetic neurotensin on two different chromatographic systems. No evidence was obtained for the presence of specific neurotensin binding sites in any of the small cell carcinoma lines examined. The results suggest that small lung cell carcinoma lines may be useful for studying the biosynthesis of human neurotensin. IMAGES:
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spelling pubmed-19768782009-09-10 Neurotensin in human small cell lung carcinoma. Goedert, M. Reeve, J. G. Emson, P. C. Bleehen, N. M. Br J Cancer Research Article High levels of neurotensin-like immunoreactivity were found in human small cell lung carcinoma lines. No immunoreactivity was present in non-small cell carcinoma lines and only low amounts in postmortem human lung tissue. The immunoreactive material co-eluted with synthetic neurotensin on two different chromatographic systems. No evidence was obtained for the presence of specific neurotensin binding sites in any of the small cell carcinoma lines examined. The results suggest that small lung cell carcinoma lines may be useful for studying the biosynthesis of human neurotensin. IMAGES: Nature Publishing Group 1984-08 /pmc/articles/PMC1976878/ /pubmed/6087865 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Goedert, M.
Reeve, J. G.
Emson, P. C.
Bleehen, N. M.
Neurotensin in human small cell lung carcinoma.
title Neurotensin in human small cell lung carcinoma.
title_full Neurotensin in human small cell lung carcinoma.
title_fullStr Neurotensin in human small cell lung carcinoma.
title_full_unstemmed Neurotensin in human small cell lung carcinoma.
title_short Neurotensin in human small cell lung carcinoma.
title_sort neurotensin in human small cell lung carcinoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976878/
https://www.ncbi.nlm.nih.gov/pubmed/6087865
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AT bleehennm neurotensininhumansmallcelllungcarcinoma

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