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Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party).
Clinico-pathological features of prognostic significance in rectal cancer are described in 824 patients who were treated at 17 centres in the Medical Research Council Trial of radiotherapy in operable cancer of the rectum. Among the pre-operative assessments the mobility of the tumour was the one mo...
Formato: | Texto |
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Lenguaje: | English |
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Nature Publishing Group
1984
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976897/ https://www.ncbi.nlm.nih.gov/pubmed/6487514 |
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collection | PubMed |
description | Clinico-pathological features of prognostic significance in rectal cancer are described in 824 patients who were treated at 17 centres in the Medical Research Council Trial of radiotherapy in operable cancer of the rectum. Among the pre-operative assessments the mobility of the tumour was the one most strongly related to prognosis. Other variables predictive of outcome were the number of involved quadrants of the rectum, the distance of the tumour from the anal verge and the age of the patient. Of assessments made at surgery or immediately after, the report of a curative operation and the Dukes' classification most closely related to prognosis. The information presented supports the idea that a pre-operative clinical staging system for rectal cancer would be feasible and useful. |
format | Text |
id | pubmed-1976897 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1984 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-19768972009-09-10 Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). Br J Cancer Research Article Clinico-pathological features of prognostic significance in rectal cancer are described in 824 patients who were treated at 17 centres in the Medical Research Council Trial of radiotherapy in operable cancer of the rectum. Among the pre-operative assessments the mobility of the tumour was the one most strongly related to prognosis. Other variables predictive of outcome were the number of involved quadrants of the rectum, the distance of the tumour from the anal verge and the age of the patient. Of assessments made at surgery or immediately after, the report of a curative operation and the Dukes' classification most closely related to prognosis. The information presented supports the idea that a pre-operative clinical staging system for rectal cancer would be feasible and useful. Nature Publishing Group 1984-10 /pmc/articles/PMC1976897/ /pubmed/6487514 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). |
title | Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). |
title_full | Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). |
title_fullStr | Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). |
title_full_unstemmed | Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). |
title_short | Clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the U.K. (Third report of the M.R.C. Trial, on behalf of the Working Party). |
title_sort | clinico-pathological features of prognostic significance in operable rectal cancer in 17 centres in the u.k. (third report of the m.r.c. trial, on behalf of the working party). |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976897/ https://www.ncbi.nlm.nih.gov/pubmed/6487514 |