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Oestrogen receptor status and the response of human breast cancer cell lines to a combination of methotrexate and 17-beta oestradiol.

We have investigated the modifying influence of 17-beta oestradiol (E2), on the cytotoxicity of methotrexate (MTX) towards two cell lines derived from human breast carcinoma. E2 (10(-7) M-10(-6) M) significantly reduced the antimetabolic effects of the drug towards an E2 non-responsive cell line, MD...

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Detalles Bibliográficos
Autores principales:	Clarke, R., Van den Berg, H. W., Kennedy, D. G., Murphy, R. F.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1985
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976963/ https://www.ncbi.nlm.nih.gov/pubmed/3970812

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