Cargando…
Antitumour imidazotetrazines, Part IX. The pharmacokinetics of mitozolomide in mice.
Mitozolomide is a novel antitumour agent showing a broad spectrum of activity against murine tumours and is currently undergoing Phase I clinical evaluation in the UK. We have conducted an animal pharmacokinetic study using male BALB/c mice as a pre-requisite to the clinical work. Mice were dosed i....
Autores principales: | Goddard, C., Slack, J. A., Stevens, M. F. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1985
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977161/ https://www.ncbi.nlm.nih.gov/pubmed/4015951 |
Ejemplares similares
-
Antitumour imidazotetrazines: past, present… and future?
por: Stevens, Malcolm F. G., et al.
Publicado: (2023) -
Plasma and tissue disposition of mitozolomide in mice.
por: Brindley, C. J., et al.
Publicado: (1986) -
The Medicinal Chemistry of Imidazotetrazine Prodrugs
por: Moody, Catherine L., et al.
Publicado: (2014) -
Mitozolomide activity on human cancer cells in vitro.
por: Erba, E., et al.
Publicado: (1986) -
Phase II evaluation of mitozolomide in ovarian cancer.
por: Harding, M., et al.
Publicado: (1988)