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Effective inhibition by low dose aminoglutethimide of peripheral aromatization in postmenopausal breast cancer patients.
Aminoglutethimide without glucocorticoid has been shown to be a clinically effective treatment for postmenopausal breast cancer in low dosage (250 mg day-1). The mechanism of action of this approach is thought to be the inhibition of peripheral aromatase, the enzyme which converts androstenedione to...
Autores principales: | Dowsett, M., Santner, S. J., Santen, R. J., Jeffcoate, S. L., Smith, I. E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1985
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977168/ https://www.ncbi.nlm.nih.gov/pubmed/4015950 |
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