Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.

Stromal progenitor cells (CFU-F) in normal mouse bone marrow were more sensitive to heat at 43 degrees C than haemopoietic progenitor cells (CFU-S and GM-CFC) by a factor of approximately 1.2. In marrow regenerating after 4.5 Gy X-rays, the changes in sensitivity were by less than a factor of 1.4 an...

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Autores principales: Wang, S. B., Hendry, J. H., Testa, N. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1985
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977179/
https://www.ncbi.nlm.nih.gov/pubmed/4015952
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author Wang, S. B.
Hendry, J. H.
Testa, N. G.
author_facet Wang, S. B.
Hendry, J. H.
Testa, N. G.
author_sort Wang, S. B.
collection PubMed
description Stromal progenitor cells (CFU-F) in normal mouse bone marrow were more sensitive to heat at 43 degrees C than haemopoietic progenitor cells (CFU-S and GM-CFC) by a factor of approximately 1.2. In marrow regenerating after 4.5 Gy X-rays, the changes in sensitivity were by less than a factor of 1.4 and the sensitivity of CFU-F changed slightly to become intermediate between that of CFU-S and GM-CFC. A comparison of sensitivities reported in the literature revealed an inexplicable large variation of up to a factor of 6 in the thermal sensitivities of CFU-S and GM-CFC.
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spelling pubmed-19771792009-09-10 Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states. Wang, S. B. Hendry, J. H. Testa, N. G. Br J Cancer Research Article Stromal progenitor cells (CFU-F) in normal mouse bone marrow were more sensitive to heat at 43 degrees C than haemopoietic progenitor cells (CFU-S and GM-CFC) by a factor of approximately 1.2. In marrow regenerating after 4.5 Gy X-rays, the changes in sensitivity were by less than a factor of 1.4 and the sensitivity of CFU-F changed slightly to become intermediate between that of CFU-S and GM-CFC. A comparison of sensitivities reported in the literature revealed an inexplicable large variation of up to a factor of 6 in the thermal sensitivities of CFU-S and GM-CFC. Nature Publishing Group 1985-07 /pmc/articles/PMC1977179/ /pubmed/4015952 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Wang, S. B.
Hendry, J. H.
Testa, N. G.
Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
title Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
title_full Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
title_fullStr Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
title_full_unstemmed Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
title_short Thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
title_sort thermal sensitivity of haemopoietic and stromal progenitor cells in different proliferative states.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977179/
https://www.ncbi.nlm.nih.gov/pubmed/4015952
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AT testang thermalsensitivityofhaemopoieticandstromalprogenitorcellsindifferentproliferativestates

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