Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.

A study of 361 female melanoma patients and age matched controls was conducted in the four western provinces of Canada. Analysis of reproductive factors showed a significant negative association between number of livebirths and risk of melanoma. The relationship persisted for superficial spreading m...

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Autores principales: Gallagher, R. P., Elwood, J. M., Hill, G. B., Coldman, A. J., Threlfall, W. J., Spinelli, J. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1985
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977278/
https://www.ncbi.nlm.nih.gov/pubmed/4074642
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author Gallagher, R. P.
Elwood, J. M.
Hill, G. B.
Coldman, A. J.
Threlfall, W. J.
Spinelli, J. J.
author_facet Gallagher, R. P.
Elwood, J. M.
Hill, G. B.
Coldman, A. J.
Threlfall, W. J.
Spinelli, J. J.
author_sort Gallagher, R. P.
collection PubMed
description A study of 361 female melanoma patients and age matched controls was conducted in the four western provinces of Canada. Analysis of reproductive factors showed a significant negative association between number of livebirths and risk of melanoma. The relationship persisted for superficial spreading melanomas after adjustment for host pigmentation factors, freckling, and educational status. An inverse association between bilateral oophorectomy and risk of superficial spreading melanoma was also seen. No association was found between risk of melanoma and age at first birth, age at menarche and age at natural menopause. No association was found between risk of superficial spreading or nodular melanoma and use of either oral contraceptives or menopausal oestrogens.
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spelling pubmed-19772782009-09-10 Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study. Gallagher, R. P. Elwood, J. M. Hill, G. B. Coldman, A. J. Threlfall, W. J. Spinelli, J. J. Br J Cancer Research Article A study of 361 female melanoma patients and age matched controls was conducted in the four western provinces of Canada. Analysis of reproductive factors showed a significant negative association between number of livebirths and risk of melanoma. The relationship persisted for superficial spreading melanomas after adjustment for host pigmentation factors, freckling, and educational status. An inverse association between bilateral oophorectomy and risk of superficial spreading melanoma was also seen. No association was found between risk of melanoma and age at first birth, age at menarche and age at natural menopause. No association was found between risk of superficial spreading or nodular melanoma and use of either oral contraceptives or menopausal oestrogens. Nature Publishing Group 1985-12 /pmc/articles/PMC1977278/ /pubmed/4074642 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Gallagher, R. P.
Elwood, J. M.
Hill, G. B.
Coldman, A. J.
Threlfall, W. J.
Spinelli, J. J.
Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
title Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
title_full Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
title_fullStr Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
title_full_unstemmed Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
title_short Reproductive factors, oral contraceptives and risk of malignant melanoma: Western Canada Melanoma Study.
title_sort reproductive factors, oral contraceptives and risk of malignant melanoma: western canada melanoma study.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977278/
https://www.ncbi.nlm.nih.gov/pubmed/4074642
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