Cargando…

The detection of alkylation damage in the DNA of human gastrointestinal tissues.

Damage arising from putative environmental sources has been found in the DNA of the gastric and colorectal mucosae of patients presenting with gastrointestinal disorders from the South Manchester area. O6-Methylguanine (O6-MeG) in the range 0.010- greater than 0.300 mu moles mole-1 adenine was heter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hall, C. N., Badawi, A. F., O'Connor, P. J., Saffhill, R.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1991
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977320/ https://www.ncbi.nlm.nih.gov/pubmed/1854628

Ejemplares similares

Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes
por: Tran, Thai Q., et al.
Publicado: (2017)

DNA direct reversal repair and alkylating agent drug resistance
por: Gutierrez, Roberto, et al.
Publicado: (2021)

Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
por: Calvo, Jennifer A., et al.
Publicado: (2013)

DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways
por: Fahrer, Jörg, et al.
Publicado: (2023)

DNA Damage Induced by Alkylating Agents and Repair Pathways
por: Kondo, Natsuko, et al.
Publicado: (2010)

Alkylated DNA damage flipping bridges base and nucleotide excision repair
por: Tubbs, Julie L., et al.
Publicado: (2009)

Ozone Chemistry and Technology. A Review of the Literature 1961-1974
por: Saffhill, R.
Publicado: (1976)

32P-post-labelling analysis of DNA adducts formed in the upper gastrointestinal tissue of mice fed bracken extract or bracken spores.
por: Povey, A. C., et al.
Publicado: (1996)

Versatile cell-based assay for measuring DNA alkylation damage and its repair
por: Li, Yong, et al.
Publicado: (2021)

The Role of DNA Mismatch Repair and Recombination in the Processing of DNA Alkylating Damage in Living Yeast Cells
por: Flores-Rozas, Hernan, et al.
Publicado: (2015)

Evolutionary analysis indicates that DNA alkylation damage is a byproduct of cytosine DNA methyltransferase activity
por: Rošić, Silvana, et al.
Publicado: (2018)

Detection of somatic changes in human cancer DNA by DNA fingerprint analysis.
por: Thein, S. L., et al.
Publicado: (1987)

A highly sensitive and specific method for quantitation of O-alkylated DNA adducts and its application to the analysis of human tissue DNA.
por: Kang, H, et al.
Publicado: (1993)

Dual chemical labeling enables nucleotide-resolution mapping of DNA abasic sites and common alkylation damage in human mitochondrial DNA
por: Liu, Chaoxing, et al.
Publicado: (2023)

Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response
por: Chen, Xi, et al.
Publicado: (2013)

The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men
por: Altakroni, B., et al.
Publicado: (2021)

Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase η
por: Koag, Myong-Chul, et al.
Publicado: (2019)

Subepidermal moisture (SEM) and bioimpedance: a literature review of a novel method for early detection of pressure‐induced tissue damage (pressure ulcers)
por: Moore, Zena, et al.
Publicado: (2016)

Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response
por: Chu, Pei-Ming, et al.
Publicado: (2011)

DNA alkylation and interstrand cross-linking by treosulfan
por: Hartley, J A, et al.
Publicado: (1999)

Repair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts
por: Bates, Steven E., et al.
Publicado: (2005)

Noninvasive methods for measuring DNA alkylation in experimental animals and humans.
por: Shuker, D E, et al.
Publicado: (1993)

MPTAC links alkylation damage signaling to sterol biosynthesis
por: Suganuma, Tamaki, et al.
Publicado: (2022)

Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems
por: Codreanu, Simona G., et al.
Publicado: (2014)

3-methyladenine-DNA-glycosylase and O6-alkyl guanine-DNA-alkyltransferase activities and sensitivity to alkylating agents in human cancer cell lines.
por: Damia, G., et al.
Publicado: (1996)

DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida
por: Jatsenko, Tatjana, et al.
Publicado: (2017)

Analysis of the Tolerance to DNA Alkylating Damage in MEC1 and RAD53 Checkpoint Mutants of Saccharomyces cerevisiae
por: Gallego-Sánchez, Alfonso, et al.
Publicado: (2013)

Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein
por: Perugino, Giuseppe, et al.
Publicado: (2015)

Quantitation and visualization of alkyl deoxynucleosides in the DNA of mammalian cells by monoclonal antibodies.
por: Adamkiewicz, J, et al.
Publicado: (1985)

Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human
por: Zanotto-Filho, Alfeu, et al.
Publicado: (2016)

Understanding the Biology of Human Interstitial Cells of Cajal in Gastrointestinal Motility
por: Foong, Daphne, et al.
Publicado: (2020)

Termination of DNA synthesis by N(6)-alkylated, not 3′-O-alkylated, photocleavable 2′-deoxyadenosine triphosphates
por: Wu, Weidong, et al.
Publicado: (2007)

Targeting neddylation induces DNA damage and checkpoint activation and sensitizes chronic lymphocytic leukemia B cells to alkylating agents
por: Paiva, C, et al.
Publicado: (2015)

Detection of human papillomavirus DNA in biopsies of human oral tissue.
por: Maitland, N. J., et al.
Publicado: (1987)

Mechanism of RNA polymerase II stalling by DNA alkylation
por: Malvezzi, Stefano, et al.
Publicado: (2017)

Alkylation of DNA In Vivo: Development of Analytical Methodology for Trace Quantitative Analysis
por: Cooks, R. G., et al.
Publicado: (1988)

PARG dysfunction enhances DNA double strand break formation in S-phase after alkylation DNA damage and augments different cell death pathways
por: Shirai, H, et al.
Publicado: (2013)

Alkylative damage of mRNA leads to ribosome stalling and rescue by trans translation in bacteria
por: Thomas, Erica N, et al.
Publicado: (2020)

Ultrasound Stress-Imaging is a Promising Tool to Detect Achilles Tendon Damage
por: O'Connor, Kathryn, et al.
Publicado: (2022)

Biosynthesis of DNA-Alkylating Antitumor Natural Products
por: Nie, Qiu-Yue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2opbm0kemsqgv6crn9pjq5l67t