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A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects.
The optimal schedule for recombinant interleukin-2 (rIL-2) administration is unclear. Because the clinical and immunological effects of prolonged continuous exposure to rIL-2 are unknown, we have conducted a phase I study to assess the toxicity and feasibility of continuous low dose infusion of rIL-...
Autores principales: | Vlasveld, L. T., Rankin, E. M., Hekman, A., Rodenhuis, S., Beijnen, J. H., Hilton, A. M., Dubbelman, A. C., Vyth-Dreese, F. A., Melief, C. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977401/ https://www.ncbi.nlm.nih.gov/pubmed/1586602 |
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