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Loss of monomorphic and polymorphic HLA antigens in metastatic breast and colon carcinoma.
MHC class I antigens are intimately involved in intercellular communication, and recognition by cytotoxic T cells. Thus tumour cells that fail to express them may be at a growth or metastatic advantage. A series of ten colorectal and ten breast carcinomas, and their respective lymph node metastases,...
Autores principales: | Goepel, J. R., Rees, R. C., Rogers, K., Stoddard, C. J., Thomas, W. E., Shepherd, L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977481/ https://www.ncbi.nlm.nih.gov/pubmed/1718386 |
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