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Cis dichlorodiammine platinum induced DNA interstrand cross-links in primary cultures of human ovarian cancer.
We quantified and examined the kinetics of DNA interstrand cross links (DNA-ISC) caused by Cis dichlorodiammine platinum (DDP) using the method of alkaline elution in 58 highly purified human ovarian tumours growing in primary culture. A large heterogeneity in both the quantity and kinetics of DDP i...
Autores principales: | Balconi, G., Pang, Y., Broggini, M., Morali, F., Marzola, M., Erba, E., Ponti, M., Spinelli, L., Mangioni, C., Redaelli, L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977530/ https://www.ncbi.nlm.nih.gov/pubmed/1892757 |
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