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Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis?
Serum laminin P1 was studied in patients with small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), respiratory infections, pulmonary fibrosis, and in normal subjects. The level of serum laminin P1 was elevated (greater than 1.27 U ml-1) in 58.9% of SCLC and in 11.5% of NSCLC patients....
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977574/ https://www.ncbi.nlm.nih.gov/pubmed/1314070 |
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author | Nakano, T. Iwahashi, N. Maeda, J. Hada, T. Higashino, K. |
author_facet | Nakano, T. Iwahashi, N. Maeda, J. Hada, T. Higashino, K. |
author_sort | Nakano, T. |
collection | PubMed |
description | Serum laminin P1 was studied in patients with small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), respiratory infections, pulmonary fibrosis, and in normal subjects. The level of serum laminin P1 was elevated (greater than 1.27 U ml-1) in 58.9% of SCLC and in 11.5% of NSCLC patients. Median value in SCLC was significantly higher than that in NSCLC (P less than 0.01), respiratory infection (P less than 0.01), and in normal subjects (P less than 0.01), but not statistically different from that in pulmonary fibrosis. The levels of serum laminin P1 in SCLC were related to therapeutic response. However, no certain correlation was established between the level of laminin P1 and the clinical stage of SCLC. |
format | Text |
id | pubmed-1977574 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1992 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-19775742009-09-10 Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? Nakano, T. Iwahashi, N. Maeda, J. Hada, T. Higashino, K. Br J Cancer Research Article Serum laminin P1 was studied in patients with small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), respiratory infections, pulmonary fibrosis, and in normal subjects. The level of serum laminin P1 was elevated (greater than 1.27 U ml-1) in 58.9% of SCLC and in 11.5% of NSCLC patients. Median value in SCLC was significantly higher than that in NSCLC (P less than 0.01), respiratory infection (P less than 0.01), and in normal subjects (P less than 0.01), but not statistically different from that in pulmonary fibrosis. The levels of serum laminin P1 in SCLC were related to therapeutic response. However, no certain correlation was established between the level of laminin P1 and the clinical stage of SCLC. Nature Publishing Group 1992-04 /pmc/articles/PMC1977574/ /pubmed/1314070 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Nakano, T. Iwahashi, N. Maeda, J. Hada, T. Higashino, K. Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? |
title | Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? |
title_full | Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? |
title_fullStr | Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? |
title_full_unstemmed | Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? |
title_short | Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? |
title_sort | serum laminin p1 in small cell lung cancer: a valuable indicator of distant metastasis? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977574/ https://www.ncbi.nlm.nih.gov/pubmed/1314070 |
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