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In vitro activity of the novel indoloquinone EO-9 and the influence of pH on cytotoxicity.

The novel indoloquinone compound EO-9 is shortly to undergo phase I clinical evaluation as a potential bioreductive drug. Preclinical studies have shown that EO-9 has greater activity against cells derived from human solid tumours than leukaemias in vitro. The results of this study extend the precli...

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Detalles Bibliográficos
Autores principales: Phillips, R. M., Hulbert, P. B., Bibby, M. C., Sleigh, N. R., Double, J. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977599/
https://www.ncbi.nlm.nih.gov/pubmed/1558788