Genetic alterations within the retinoblastoma locus in colorectal carcinomas. Relation to DNA ploidy pattern studied by flow cytometric analysis.

Alterations within the retinoblastoma (Rb) gene, as detected by the VNTR probe p68RS2.0, and flow cytometric DNA pattern have been analysed in 255 colorectal carcinomas. A total of 35.3% of the tumours had alterations within the Rb gene. Amplification of one allele was demonstrated in 29.5% of the t...

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Detalles Bibliográficos
Autores principales: Meling, G. I., Lothe, R. A., Børresen, A. L., Hauge, S., Graue, C., Clausen, O. P., Rognum, T. O.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977625/
https://www.ncbi.nlm.nih.gov/pubmed/1911187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977625/
https://www.ncbi.nlm.nih.gov/pubmed/1911187

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