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A less toxic regimen of 5-fluorouracil and high-dose folinic acid for advanced gastrointestinal adenocarcinomas.

The combination of high-dose folinic acid with 5-fluorouracil has shown improved response rates in several trials in advanced colorectal carcinoma. This however is at the expense of increased toxicity: regimens using weekly bolus injections produce diarrhoea in most patients and occasional toxic dea...

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Detalles Bibliográficos
Autores principales:	Johnson, P. W., Thompson, P. I., Seymour, M. T., Deasy, N. P., Thuraisingham, R. C., Slevin, M. L., Wrigley, P. F.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1991
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977639/ https://www.ncbi.nlm.nih.gov/pubmed/1911206

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