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A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer.
Lonidamine is a substituted indazole carboxylic acid with a unique mechanism of action and early clinical studies have reported anti-tumour activity. In a phase II study 32 patients with previously treated advanced breast cancer were given Lonidamine in a daily divided oral dose of 600 mg. Of 28 pat...
Autores principales: | Mansi, J. L., de Graeff, A., Newell, D. R., Glaholm, J., Button, D., Leach, M. O., Payne, G., Smith, I. E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977661/ https://www.ncbi.nlm.nih.gov/pubmed/1911204 |
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