Increasing the effective concentration of melphalan in experimental rat liver tumours: comparison of isolated liver perfusion and hepatic artery infusion.

Regional chemotherapy allows further exploitation of the steep dose response curve of most chemotherapeutic agents, while systemic toxicity remains tolerable. We investigated the difference in maximally tolerated dose, pharmacokinetics and antitumour effect comparing administration of melphalan as a...

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Detalles Bibliográficos
Autores principales: Marinelli, A., van Dierendonck, J. H., van Brakel, G. M., Irth, H., Kuppen, P. J., Tjaden, U. R., van de Velde, C. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1977872/
https://www.ncbi.nlm.nih.gov/pubmed/1764369

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